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Tea, Caffeine, Genetics, and Cultural Influences

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In various tea forums, I see questions about caffeine in tea, caffeine consumption, etc. Some people seem to drink a lot and not be affected; some people are very sensitive to the tiniest amount of caffeine. Everyone is different and one person's tea consumption is going to be different from everyone elses. Is it a matter of genetics or culture? Turns out...a bit of both!